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Brazilian Journal of Clinical Medicine and Review

Original research

Vol. 3 No. 1 (2025): January/December - 2025

Biological Age and its Relationship with Mortality of Elderly People with COVID-19 in a Public Hospital in Northeastern Brazil

DOI
https://doi.org/10.52600/2965-0968.bjcmr.2025.3.1.bjcmr19
Submitted
August 13, 2024
Published
2024-10-31

Abstract

To estimate the biological age of elderly people hospitalized with a confirmed diagnosis of COVID-19, and its relationship with mortality. A retrospective and quantitative cohort study, carried out in a public hospital in the city of Recife-PE, from April 2020 to April 2021, with 115 elderly people of both sexes. The biological age of the participants was estimated by a calculator that uses nine laboratory blood tests and mortality was analyzed. Of the 115 elderly people hospitalized in a public referral hospital for COVID-19, the predominant gender was male, age ≥ 70 years, black/brown skin color, illiterate/low education, with a partner. Arterial hypertension and diabetes were the most common comorbidities in the study population. Regarding ICU admission, use of mechanical ventilation, length of ICU stays and mortality, there was a significant association with premature aging (p-value = 0.009, 0.009, 0.042 and 0.009 respectively). The biological Age was able to predict clinical outcomes, proving to be superior to Chronological Age.

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