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Brazilian Journal of Clinical Medicine and Review

Mini Review

Vol. 2 No. 4 (2024): October/December - 2024

Metabolic syndrome as the main risk factor associated with the development of type 2 Diabetes Mellitus and cardiovascular pathologies

DOI
https://doi.org/10.52600/2965-0968.bjcmr.2024.2.4.23-33
Submitted
January 18, 2024
Published
2024-02-26

Abstract

The objective of this study is to gather information that corroborates that metabolic syndrome acts as the main risk factor associated with the development of type 2 diabetes mellitus and cardiovascular diseases. An integrative review, carried out between the months of August and December 2023, using the digital library Scientific Electronic Library Online (SciELO), the Virtual Health Library (VHL) and PUBMED in the databases using the Boolean operators: AND and OR. The results were obtained through management with the Rayyan 16 QCRI application and were structured in PRISMA flowcharts. With the search in the databases, 223 articles were found, of which 37 were selected for reading and, according to the objective of the present work, 23 articles were included in the research. In the studies observed, it is concluded that to prevent metabolic syndrome it is essential to adopt a healthy lifestyle, weight control, regular physical activity and frequent monitoring of blood glucose levels and regularly consult a health professional to adjust treatment. and ensure adherence to pharmacological and non-pharmacological measures.

References

  1. Akrami A, Nikaein F, Babajafari S, Faghih S, Yarmohammadi H. Comparison of the effects of flaxseed oil and sunflower seed oil consumption on serum glucose, lipid profile, blood pressure, and lipid peroxidation in patients with metabolic syndrome. J Clin Lipidol. 2018 Jan;12(1):70-77. doi: 10.1016/j.jacl.2017.11.004.
  2. American Heart Association. What is Metabolic Syndrome? [Internet]. 2017 Oct 20 [cited 2024 Jan 10]. Available from: https://www.heart.org/en/health-topics/metabolic-syndrome/about-metabolic-syndrome.
  3. Andrade LJO, Oliveira GCM, Oliveira LM. The connection between bile acids and type 2 diabetes mellitus - a review. Arq Gastroenterol. 2023 Oct;60(4):536-42.
  4. Batista da Silva J, de Melo EM, Micussi MT, Dantas de Azevedo G, Lemos TM, Spyrides MH, Arrais RF, Maranhão TM. Prevalência da síndrome metabólica nos estágios pubertários de escolares do sexo feminino. Rev Salud Publica (Bogota). 2016 Jun;18(3):425-36. Portuguese. doi: 10.15446/rsap.v18n3.43065. PMID: 28453105.
  5. Behrens M. Educação Transformadora. Rev Port Educ. 2020.
  6. Castanho GK, Marsola FC, Mclellan KC, Nicola M, Moreto F, Burini RC. Consumo de frutas, verduras e legumes associado à Síndrome Metabólica e seus componentes em amostra populacional adulta. Cien Saude Colet. 2013 Feb;18(2):385-92. Portu-guese. doi: 10.1590/s1413-81232013000200010. PMID: 23358764.
  7. Castro RM, Silva AM, Silva AK, Araújo BF, Maluf BV, Franco JC. Diabetes mellitus e suas complicações - uma revisão sis-temática e informativa. Braz J Health Rev [Internet]. 2021 [cited 2024 Jan 16];4(1):3349-91. Available from: https://doi.org/10.34119/bjhrv4n1-263.
  8. Chacra AP. Dislipidemia diabética. Soc Cardiol Estado São Paulo [Internet]. 2016 Jul [cited 2024 Jan 15];26(3):195-204.
  9. Correa-Bautista JE, González-Ruíz K, Vivas A, Triana-Reina HR, Martínez-Torres J, Prieto-Benavides DH, Carrillo HA, Ra-mos-Sepúlveda JA, Afanador-Rodríguez MI, Villa-González E, García-Hermoso A, Ramírez-Vélez R. Comparação de três índices de adiposidade e pontos de corte para predizer síndrome metabólica em universitários. Metab Syndr Relat Disord. 2017 Oct;15(7):363-70. doi: 10.1089/met.2017.0016.
  10. Cortez-Dias N, Martins SR, Belo A, Fiuza M; Investigadores do Estudo VALSIM. Associação de fatores de risco metabólicos com hipertensão não controlada: comparação das várias definições de síndrome metabólica. J Hypertens. 2013 Oct;31(10):1991-7. doi: 10.1097/HJH.0b013e32836342f7. PMID: 23811998.
  11. Costa-Vieira D, Monteiro R, Martins MJ. Metabolic syndrome features: Is there a modulation role by mineral water con-sumption? A review. Nutrients. 2019 May;11(5):1141. doi: 10.3390/nu11051141.
  12. Farias DL, Tibana RA, Teixeira TG, Vieira DC, Tarja V, Nascimento DD, Silva AD, Funghetto SS, Coura MA, Valduga R, Karnikowski MG, Prestes J. Elderly women with metabolic syndrome present higher cardiovascular risk and lower relative muscle strength. Einstein (Sao Paulo). 2013 Jun;11(2):174-9. doi: 10.1590/s1679-45082013000200007.
  13. Freire JAP, Frota KdMG, da Silva Júnior AJ. Fatores de risco cardiovascular e prevalência de síndrome metabólica em idosos. Rev Bras Promoc Saude. 2014;27(4):477-84. doi: 10.1590/2177-9465-EAN-2020-0055.
  14. Harraqui K, Oudghiri DE, Mrabti HN, Hannoun Z, Lee LH, Assaggaf H, Qasem A, Goh KW, Ming LC, Tan CS, Bouyahya A, Bour A. Associação entre atividade física, composição corporal e distúrbios metabólicos em mulheres de meia-idade de Ksar el Kebir (Marrocos). Int J Environ Res Public Health. 2023;20(3):1739. doi: 10.3390/ijerph20031739.
  15. Jerez Fernández CI, Medina Pereira YA, Ortiz Chang AS, González Olmedo SI, Aguirre Gaete MC. Fisiopatología y altera-ciones clínicas de la diabetes mellitus tipo 2. Nova. 2022 Sep 13;20(38):65-103. doi: 10.22490/24629448.6184.
  16. Madeira Timóteo Dias IC, Carneiro Carvalho E, Cascardo Marins AL, Serpa Franco A, Dantas de Oliveira Souza NV, Silva de Andrade KB. Avaliação de risco para tromboembolismo venoso: estudo bibliométrico para a prática clínica de cardioncologia. Rev Enferm Atual Derme. 2022 Sep 15;96(39). doi: 10.31011/reaid-2022-v.96-n.39-art.1438.
  17. Mendes KS, et al. Use of the bibliographic reference manager in the selection of primary studies in integrative reviews. Texto Contexto Enferm. 2019;28(4).
  18. Moore JX, Chaudhary N, Akinyemiju T. Metabolic syndrome prevalence by race/ethnicity and sex in the United States, National Health and Nutrition Examination Survey, 1988–2012. Prev Chronic Dis. 2017 Mar 16;14:160287. Available from: https://www.cdc.gov/pcd/issues/2017/16_0287.htm.
  19. Nascimento OJ, Pupe CC, Cavalcanti EB. Diabetic neuropathy. Rev Dor. 2016;17. doi: 10.5935/1806-0013.20160047.
  20. NHLBI, NIH. What Is Metabolic Syndrome? [Internet]. 2022 May 18 [cited 2024 Jan 10]. Available from: https://www.nhlbi.nih.gov/health/metabolic-syndrome.
  21. Oliveira LVA, Santos BNSD, Machado ÍE, Malta DC, Velasquez-Melendez G, Felisbino-Mendes MS. Prevalence of the meta-bolic syndrome and its components in the Brazilian adult population. Cien Saude Colet. 2020 Nov;25(11):4269-80. Portuguese, English. doi: 10.1590/1413-812320202511.31202020. PMID: 33175036.
  22. Paiva MH, et al. Prevalence of metabolic syndrome and its components in Brazilian adolescents: a systematic review and meta-analysis. Rev Paul Pediatr. 2023;41:e2021145.
  23. Pérez-Martínez P, Mikhailidis DP, Athyros VG, Bullo M, Couture P, Covas MI, et al. Lifestyle recommendations for the prevention and management of metabolic syndrome: an international panel recommendation. Nutr Rev. 2017 May;75(5):307–26. Available from: https://academic.oup.com/nutritionreviews/article/75/5/307/3830251. doi: 10.1093/nutrit/nux014.
  24. Piñeros-Garzón FS, Rodríguez-Hernández JM. Factores de riesgo asociados al control glucémico y síndrome metabólico en pacientes con diabetes mellitus tipo 2. Villavicencio, Colombia. Univ Salud. 2019;21(1):61-71. DOI: 10.22267/rus.192101.140.
  25. Prevalência da Síndrome Metabólica e seus componentes na população adulta brasileira. Ciênc Saúde Colet. 2020 Nov;25(11):4269-4280.
  26. Siqueira Valadares LT, de Souza LSB, Salgado Júnior VA, de Freitas Bonomo L, de Macedo LR, Silva M. Prevalence of metabolic syndrome in Brazilian adults in the last 10 years: a systematic review and meta-analysis. BMC Public Health. 2022 Feb 16;22(1):327. doi: 10.1186/s12889-022-12753-5. PMID: 35172790; PMCID: PMC8848905.
  27. The association between metabolic syndrome and major adverse cardiac and cerebrovascular events in patients with acute coronary syndrome undergoing percutaneous coronary intervention. Sci Rep. 2024 Jan 6;14(1):697. Available from: https://pesquisa.bvsalud.org/portal/resource/es/mdl-38184738. Accessed on: Jan 17, 2024.
  28. Whitfield JB, Heath AC, Madden PAF, Pergadia ML, Montgomery GW, Martin NG. Metabolic and Biochemical Effects of Low-to-Moderate Alcohol Consumption. Alcohol Clin Exp Res. 2013 Apr;37(4):575–86. doi: 10.1111/acer.12015.
  29. Xiao J, Chu M, Shen H, Ren W, Li Z, Hua T, Xu H, Liang Y, Gao Y, Zhuang X. Relationship of "weekend warrior" and regular physical activity patterns with metabolic syndrome and its diseases in rural Chinese adults. J Sports Sci. 2018;36(17):1963–1971. doi: 10.1080/02640414.2018.1428883.
  30. Xiao J, Hua T, Shen H, Zhang M, Wang XJ, Gao YX, Lu Q, Wu C. Associations of metabolic disorder factors with the risk of uncontrolled hypertension: a follow-up cohort in rural China. Sci Rep. 2017;7:743. doi: 10.1038/s41598-017-00789-2.

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