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Brazilian Journal of Clinical Medicine and Review

Original research

Vol. 2 No. 2 (2024): April/June - 2024

Nocturnal Blood Pressure Patterns in Hypertensive patients with Obstructive Sleep Apnea Syndrome in Angola

DOI
https://doi.org/10.52600/2965-0968.bjcmr.2024.2.2.25-34
Submitted
October 13, 2023
Published
2023-12-05

Abstract

The main cardiovascular consequence of Obstructive Sleep Apnea Syndrome (OSAS) is arterial hypertension (AH), considered since 2003 a second cause of AH. This study aimed to evaluate nocturnal blood pressure patterns (BPP) in hypertensive patients with OSAS in Angola. A descriptive, cross-sectional observational study was carried out in a private clinic in Angola. Demographic and clinical variables, polysomnography, and ABPM parameters were included. Patients were classified as a dippers, non-dippers, and reverse dippers. One-way ANOVA test, Kruskal-Walli’s test, and chi-square test were used as appropriate. The sample consisted of 70 individuals: 39(55.7%) were male. The mean age was 53.63±9.14 years and the BMI was 35.82 ± 6.57 kg/m2. An association between patients with a past medical history of hypertension and BPP was found (p<0.05). Mean O2 saturation was significantly lower in the reverse dippers (p=0.25). Although insignificantly, the dippers were younger and less obese. In contrast, the proportion of smokers and diabetics was higher in the reverse dippers. No correlation was found between the apnea-hypopnea index, the mean blood pressure, and the Epworth sleepiness scale. In the present study, the prevalence of non-dipping and reverse dipping patterns was high. It needs to be confirmed with future prospective studies.

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