The conference provides an introduction to the Universal Declaration on Bioethics and Human Rights approved by UNESCO in 2005. It begins by analyzing the historical and geopolitical context in which it was approved. and what were the global debates that the standard includes. The different stages of the consultation are analyzed that led to its approval from the preparation of the first draft. The ethical-legal roots are presented and the background on which it bases its principles and a description of the novelties is presented that the Declaration offers with respect to other regulations for multinational research. A detail about your articles and their contents to conclude with the way in which you can ensure your due implementation by the states in terms of public policies and regulations.