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Brazilian Journal of Clinical Medicine and Review

Correspondence

Vol. 4 No. 1 (2026): January/December - 2026

Hemostatic Resuscitation in Severe Trauma: Early Administration of Tranexamic Acid Integrated with Massive Transfusion Protocols

DOI
https://doi.org/10.52600/2965-0968.bjcmr.2026.4.1.bjcmr49
Submitted
November 16, 2025
Published
2025-12-14

References

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  2. Cap AP, Simmons JW, Spinella PC. Transfusion ratios in massive transfusion: current evidence and future directions. Transfusion. 2023;63(4):987-995. doi:10.1111/trf.17341.
  3. Holcomb JB, Pati S, Johansson PI. TEG-guided resuscitation in trauma: outcomes and practical applications. Crit Care Med. 2023;51(2):201-210. doi:10.1097/CCM.0000000000005831.
  4. CRASH-2 Trial Collaborators. Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients. Lancet. 2010;376(9734):23-32. doi:10.1016/S0140-6736(10)60835-5.
  5. CRASH-3 Trial Collaborators. Effects of early tranexamic acid in traumatic brain injury. Lancet. 2020;394(10210):1713-1723. doi:10.1016/S0140-6736(19)32233-0.
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