Use of creatine for muscle hypertrophy in resistance training practitioners: a narrative review

Authors

  • Francisco Fábio Félix Macêdo Specialization in Nutrition and Physical Exercise, State University of Ceará
  • Francisco Rafael Oliveira da Silva Post-Graduate Program of Morphofunctional Sciences, Federal University of Ceará https://orcid.org/0000-0002-9550-4898

DOI:

https://doi.org/10.52600/2965-0968.bjcmr.2023.1.2.31-35

Keywords:

Creatine, Physical Exercise, Resistance Training, Supplementation, Ergogenics

Abstract

Creatine is a natural substance found in muscles that has gained popularity among physical activity practitioners, especially bodybuilders, due to its various benefits, including improved muscle tone, increased strength, optimized recovery, and muscle mass gain. The most common form of creatine is monohydrate, which is cost-effective and efficacious. However, the unguided use of supplements, including α-methyl guanidinoacetic acid, which has possible pharmacological, nutritional, and physiological effects on fast muscle energy and muscle hypertrophy, is common among exercise practitioners. On the other hand, creatine, also a widely used ergogenic, is capable of rapidly renewing muscular energy and increasing strength and total lean body mass. However, the use of dietary supplements such as creatine should be done with caution and accompanied by a specialized professional capable of establishing parameters that best meet the individual needs of each athlete or individual seeking muscle hypertrophy. It is essential to discuss the factors associated with the development of lean muscle mass, including creatine supplementation, considering its nutritional and pharmacological implications. Therefore, this narrative review aims to analyze the role of creatine as an ergogenic dietary supplement for muscle hypertrophy and identify the risks associated with its consumption.

Author Biographies

Francisco Fábio Félix Macêdo, Specialization in Nutrition and Physical Exercise, State University of Ceará

Specialization in Nutrition and Physical Exercise, State University of Ceará, Ceará, Brazil.

Francisco Rafael Oliveira da Silva, Post-Graduate Program of Morphofunctional Sciences, Federal University of Ceará

Specialization in Nutrition and Physical Exercise, State University of Ceará, Ceará, Brazil.

Post-Graduate Program of Morphofunctional Sciences, Federal University of Ceará, Ceará, Brazil.

References

Leite MSR, Machado DAL, Vieira ALC, et al. Creatina: estratégia ergogênica no meio esportivo. Uma breve revisão. Rev Atenção à Saúde. 2015 Jan-Mar;13(43):52-60.

Menezes CS, Moraes BA, Linhares PSD. Creatina: efeitos da suplementação. Rev Referências em Saúde da Faculdade Estácio de Sá de Goiás. 2020 Aug-Dec;3(2):122-126.

Zardo EC. Relação entre o uso de creatina diária e na fase de saturação no desempenho de praticantes de exercício físico [Relationship between daily creatine supplementation and saturation phase on the performance of physical exercise practi-tioners]. Monografia (Graduação em Nutrição) – Faculdade de Ciências da Educação e Saúde, Centro Universitário de Brasília. Brasília, 2019. p. 17.

Oliveira LM, Azevedo MO, Cardoso CKS. Efeitos da suplementação de creatina sobre a composição corporal de praticantes de exercícios físicos. Revista Brasileira de Nutrição Esportiva. 2017 Jan/Fev;11(61):10-15.

Martins YLX, Lima MF, Ramos JL, Marins JCB. Efeitos de diferentes formas de suplementação de creatina em praticantes de musculação: estudo exploratório. Rev Bras Nutr Esportiva. 2019 Nov-Dec;13(82):854-863.

Paula AB, Azevedo BM. Suplementação de creatina e a eficácia no aumento de massa magra, força e desempenho em trei-namentos de alta intensidade. Revista Multidisciplinar da Saúde. 2020;2(2):01-17.

Zanelli JCS, Cordeiro BA, Beserra BTS, Trindade EBSM. Creatina e treinamento resistido: efeito na hidratação e massa corporal magra. Revista Brasileira de Medicina e Esporte. 2015 Jan/Fev;21(1).

Teixeira Y, Almeida PT, Pereira TC, Barreto JAPS, Menezes RSM, Silva CL, Bezerra PS, Sousa LdeN, Silva PN, Sousa SM, Lima Júnior JCCde, Oliveira HDM de, Oliveira PLde, Silva EBda, Bellas JMAde, Pereira DF, Furtado YRAL, Oliveira AHde, Andrade AO, Landim HS, Lima AET, Macedo LRde, Canuto AFA. Effects of Creatine Supplementation on Physical Performance: An integrative literature review. Research, Society and Development. 2020;9(7):1-14.

Antonio J, Candow DGg, Forbes SC, et al. Common questions and misconceptions about creatine supplementation: what does the scientific evidence really show? J Int Soc Sports Nutr. 2021 Feb 16;18(1):13. doi: 10.1186/s12970-021-00412-w.

Avgerinos KI, Spyrou N, Bougioukas KI, Kapogiannis D. Effects of creatine supplementation on cognitive function of healthy individuals: A systematic review of randomized controlled trials. Exp Gerontol. 2018 Jul;108:166-173.

Mcardle WD, Katch FI, Katch VL. Fisiologia do exercício: energia, nutrição e desempenho. 6ª ed. Rio de Janeiro: Guanabara Koogan; 2008.

Kreider RB, Kalman DS, Antonio J, et al. International Society of Sports Nutrition position stand: Safety and efficacy of creatine supplementation in exercise, sport, and medicine. J Int Soc Sports Nutr. 2017 Jun 13;14:18. doi: 10.1186/s12970-017-0173-z.

Brasil. Ministério da Saúde. Instrução Normativa – IN Nº 28, DE 26 DE JULHO DE 2018. Estabelece as listas de constituintes, de limites de uso, de alegações e de rotulagem complementar dos suplementos alimentares. Diário Oficial da União. 2018 Jul 27;141.

Brioschi FR, Hemerly HM, Bindaco ES. Efeitos ergogênicos da creatina. Rev Conhecimento em Destaque. 2019;8(19):150-159.

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Published

2023-03-14

Issue

Section

Health Review