The pandemic has highlighted that humanization and care must be inseparable. The abrupt change in the global health landscape underscored the fundamental importance of empathetic human action, extending beyond healthcare equipment. Machines cannot replace the nurse-patient relationship in the pandemic context; thus, the theme of humanization in healthcare becomes crucial for care practices. From this perspective, the aim was to emphasize the importance of nursing care in providing humanized support to patients and their families in the face of COVID-19. This research is of a bibliographic nature. Cross-references were made using the following keywords: "Humanization of Care"; "Nursing"; "Communication"; "Pandemic"; "Covid-19"; and "Patients," in the LILACS, BVS, SciELO, and SANARE databases. Six articles were selected. The results revealed that the humanization of care was essential for establishing a bond of trust and empathy between the healthcare professional and the patient, making the care effective and transcending beyond the biological dimension. It addressed the patient's physical, mental, and emotional needs.